Tirzepatide 60mg Protocol

Key Benefits

Dual GIP/GLP-1 receptor agonist for metabolic health

Superior body composition & fat loss outcomes

Improves insulin sensitivity & glucose regulation

Appetite suppression; reduces caloric intake naturally

Sustained effects — half-life ~5 days, weekly dosing

Reconstitution

20 mg/mL

Concentration

0.2 mg

Per Unit (U-100)

28 days

Use Within

Standard Titration — Once Weekly (6 Phases)

Weeks 1–42.5 mg — Tolerability12.5 u

Weeks 5–85 mg — 1st Maintenance25 u

Weeks 9–127.5 mg — Transitional37.5 u

Weeks 13–1610 mg — 2nd Maintenance50 u

Weeks 17–2012.5 mg — Transitional62.5 u

Weeks 21+15 mg — Maximum Dose75 u

Min 4 weeks between dose increases. Do NOT double up on missed doses.

Reconstitution Steps

3.0 mL

Bacteriostatic (BAC) Water Needed

Add to the 60mg vial → final concentration 20 mg/mL

Sanitize

Swab both vial stoppers with fresh alcohol and let them dry.

Draw Water

Draw exactly 3.0 mL bacteriostatic (BAC) water with a sterile syringe.

Add Slowly

Inject the water down the inner vial wall — never directly onto the powder.

Dissolve

Gently swirl or roll — do not shake. Wait until fully clear.

Label & Store

Refrigerate at 36–46°F, date the vial, use within 28 days.

60mg Vial Supply Planning (20 mg/mL · 3.0 mL per vial)

Duration	Through Dose	Cumulative Total	60mg Vials
4 weeks	2.5 mg	10 mg	1 vial
8 weeks	5 mg	30 mg	1 vial
12 weeks	7.5 mg	60 mg	1 vial
16 weeks	10 mg	100 mg	2 vials
20 weeks	12.5 mg	150 mg	3 vials
24 weeks (full)	15 mg max	210 mg	4 vials

Pharmacokinetics

~5 days

Half-Life

4 weeks

Steady State

1.6×

Accumulation Ratio

96 hrs

Missed Dose Window

Injection Schedule — Once Weekly

SAME DAY EACH WEEK — NEVER DOUBLE DOSE

Subcutaneous

45–90° angle, abdomen preferred

Rotate Sites

Abdomen, Thigh, Upper arm

Storage

−4°F

Lyophilized 12+ mo

36–46°F

Reconstituted 28 days

No Freeze

Reconstituted solution

Protect

From Light Always

Contraindicated: MTC history, MEN2, pancreatitis, type 1 diabetes, pregnancy, under 18.