PL
Primo Labs
primolabs.co/protocols
Retatrutide
Transform · Evolve · Extend
20mg
Vial Size
Key Benefits
Triple receptor agonist — GLP-1, GIP & glucagon
Supports significant fat loss & body recomposition
Improves insulin sensitivity & metabolic health
Appetite suppression & reduced caloric intake
Extended cycles: minimum 24 weeks, typical 48 weeks
Reconstitution
10 mg/mL
Concentration
100 mcg
Per Unit (U-100)
4 weeks
Use Within
Standard / Gradual — Once Weekly
Weeks 1–4
2 mg (2,000 mcg)
20 units
Weeks 5–8
4 mg (4,000 mcg)
40 units
Weeks 9–12
6 mg (6,000 mcg)
60 units
Weeks 13+
8 mg (8,000 mcg)
80 units
Advanced / Aggressive — Once Weekly
Weeks 1–4
2 mg (2,000 mcg)
20 units
Weeks 5–8
4 mg (4,000 mcg)
40 units
Weeks 9–12
8 mg (8,000 mcg)
80 units
Weeks 13+
12 mg (12,000 mcg)
120 units
Reconstitution Steps
2.0 mL
Bacteriostatic (BAC) Water Needed
Add to the 20mg vial → final concentration
10 mg/mL
1
Sanitize
Swab both vial stoppers with fresh alcohol and let them dry.
2
Draw Water
Draw exactly
2.0 mL
bacteriostatic (BAC) water with a sterile syringe.
3
Add Slowly
Inject the water down the inner vial wall — never directly onto the powder.
4
Dissolve
Gently swirl or roll — do not shake. Wait until fully clear.
5
Label & Store
Refrigerate at 36–46°F, date the vial, use within
4 weeks
.
Supply Planning
Duration
Protocol
Vials (20mg)
Syringes
12 Weeks
Standard
3 vials
12–24
24 Weeks
Standard
8 vials
24–48
12 Weeks
Aggressive
3 vials
12–24
Common Side Effects (Dose-Escalation Related)
Nausea
Mild–moderate; worst during escalation
Vomiting
More common at higher doses (8–12mg)
Diarrhea
Typically transient & dose-dependent
Injection Schedule
ONCE WEEKLY — SAME DAY EACH WEEK
M
T
W
TH
F
SA
SU
Choose any consistent day
Subcutaneous
45–90° angle, abdomen preferred
Rotate Sites
Abdomen, Thigh, Upper arm
Storage
−4°F
Lyophilized (24 mo)
36–46°F
Reconstituted (4 wks)
Protect
From Light Always
1× Thaw
Extended: −4°F aliquot
Volumes >1.0 mL: split into 2 injections at separate sites.